| TOX Notes | Archived News Home / In Vitro Sensitization Assay (IVSA) In Vitro Sensitization Assay (IVSA) Skin Sensitization utilizing 3D Human Tissue Constructs MB Research offers... developed and in vitro assay that uses a 3D human differentiated epidermal tissue model that closely parallels human skin, that is composed of human-derived epidermal keratinocytes... cultured to form a multilayered, highly differentiated model of the human epidermis. Keratinocytes are the outermost component of skin and provide the first line of defense to chemical...

in vitro toxicology tests for dermal corrosivity, skin irritation, and phototoxicity. Applications: product development/efficacy, claims substantiation, safety assessment, and target... of MatTek Corporation. Other Links MatTek EpiDerm Video - An In Vitro Skin Irritation Test (SIT) using the EpiDerm Reconstructed Human Epidermal (RHE) Model site map | contact | 2010 MB Research Laboratories ...

are representative of the eye and skin epithelium Human cells are derived from neonatal, adolescent, or aged donors Cytokine expression or release (LDH, PGE-2, interleukins) can... Dimensional Human Skin Equivalent Systems The 3D models available at MB Research (MatTek EpiDerm and SkinEthic systems) allow the application of the test material directly... to the "skin" surface and permit the assessment of dermal toxicity via a wide variety of parameters. Cytotoxicity via MTT, neutral red viability assay, or flow cytometry Histological...

of Toxicology Annual Meeting in Seattle. To view and print our posters, please click on the links below. A 3D skin model for cosmetic, chemical and medical device phototoxicity testing.... -Further validation of the Enhance Phototoxicity screening Assay in Reconstituted Skin (EPARS), a highly predictive phototoxicity assay, with endpoints of inflammatory mediator... Annual Meeting in Charolette. "Comparison of in vitro phototoxicity Test Methods: 3T3 NRU PT vs. Enhanced Phototoxicity screening Assay in Reconstituted Skin (EPARS...

detergents, dishwashing liquids, and skin lotions. A plot of the in vivo and calculated in vitro Draize scores, when correlated to the line In Vivo Draize (MMAS) = In Vitro Calculated...