). The natural product-based feedstock generated by ReBACS offers a complex and rich structural diversity, simplifies the synthetic challenge in drug discovery and increases... the probability of generating new lead compounds. We facilitate the identification of lead compounds, the preparation of focused libraries and the efficient scale up of lead production.... Based on our natural product-like compound arrays, Promiliad Biopharma has established internal drug discovery programs that are focused on the development of new antibacterial and antifungal agents. ...

of these compounds will be a pre-clinical testing to show efficacy in bacterial infection models. 2006 August - Promiliad Biopharma was awarded a Phase I STTR award to develop new inhibitors... of Health to continue our development of natural product-like libraries of new chemical entities. This award will allow us to expand our compound collection to a size needed... for commercialization. 2005 July - Promiliad Biopharma was awarded a Phase I STTR grant from the National Institutes of Health to study methods to introduce chemical diversity into the sugar...