Property Neurogenesis The process of forming new neurons from the brains own neuronal stem/progenitor cells is called neurogenesis. Surprisingly, this event continues to proceed well... into adulthood. In particular, neurogenesis is known for taking place in the hippocampus, one of two major neuronal stem/progenitor cell niches, which is critical for learning... when producing new neurons from neuronal progenitor cells in the hippocampus. Therefore, the brain must require and utilize these nascent neurons into adulthood, if the brain...

species also tolerates prolonged periods of restricted cerebral blood flow (ischemia) with minimal neuronal cell death. This may be an evolved response to pronounced fluctuations... by preparing hippocampal neuronal stem cells obtained from adult Arctic ground squirrels. We found that these neuronal stem cells produce neurons that are less susceptible to stroke-like... conditions than other neuronal cells, including human neurons. The proteins that confer this tolerance to AGS neurons provide potential targets for the development of novel stroke...

. These, small-molecule, therapeutic candidates all promote new neurons from the brains own neuronal stem/progenitor cell populations. Preclinical studies of these candidates... neuron numbers in the brain, to improve critical function and to diminish loss of neurons due to disease progression. This ensures that each therapy is optimal for the indication. NEWS... for stimulating neurogenesis and inhibiting neuronal degeneration. Patent claims had previously been issued in the US and Russia back in 2011. Feb 2012 The founder and President...

proliferation of human neuronal progenitor cells and to promote differentiation into mature neurons in a dose dependent manner. Such "screens" consist of specially designed cell-culture...