antigens. Importantly, this antigen loss, dubbed "antigen- silencing," is the result of gene regulatory events that are reversible. CytoCure's research and development programs have...CytoCure Mission CytoCure Novel Cancer Therapeutics--Overcoming Antigen Silencing CytoCure HomeCytoCure MissionCytoCure TechnologyClinical TrialsContact Information CytoCure... identified numerous compounds which affect known cellular processes that can be used to up-regulate antigen expression.CytoCure has submitted a patent application that claims the use...

among tumors. CytoCure scientists have shown that the loss of these antigens is often due to reversible gene regulation. Proprietary CytoCure technology is based on overcoming tumor...-produced factors that induce loss of tumor antigens, thus assuring that the tumor cells continue to express the antigenic structures that will allow the immune response to destroy... all tumor cells in the tumor mass. Since the loss of tumor associated antigens currently represents a significant limitation to the success of cancer vaccines, the re-introduction...