Innovative Biologics Inc., IBI, anti-microbial research related to anthrax. Home Page Our Technology Our People Papers And Links Contact Us >Innovative Biologics was established... in December, 2003 and its research is supported by the NIH SBIR grants. Our company islocated in Herndon, Virginia. Our focus is to search for new anti-microbial drugs targeting... bacterial toxins. [ Home Page | Our Technology | Our People | Papers And Links | Contact Us ] Copyright 2005. Created and Maintained by WSI This site is optimized for Netscape 5 and Internet Explorer 5 or higher. Please download an updated version now. ...

to inhibit lethal toxin action. Several compounds displayed anti-toxin activity at low micromolar concentrations in cell-based assays. Preliminary toxicity and efficacy studies in rodents... are the cytotoxic effect of anthrax toxin, and bacteremia leading to oxygen and nutritional substance deprivation, accumulation of various bacterial and host toxic products with eventual organ... failure and death. Our research is based on the premise that the simultaneous blocking of bacterial growth by antibiotics and inhibition of anthrax toxin action would be beneficial...